Lichen planus
https://en.wikipedia.org/wiki/Lichen_planus
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References
Cutaneous and mucosal lichen planus: a comprehensive review of clinical subtypes, risk factors, diagnosis, and prognosis 24672362 NIH
Lichen planus (LP) o se maʻi inflammatory chronic (chronic inflammatory disease) e tele ona aafia ai tagata matutua i le ogatotonu o latou tausaga. E mafai ona faʻaalia i luga o le paʻu po’o le mucous membranes e pei o le gutu, le vaʻa (vulvovaginal), le esophagus, le pusa leo (larynx), ma le ufiufi mata (conjunctiva). E ese‑ese foʻi foʻi le auala e aafia ai le LP; e mafai ona aafia le paʻu po’o le mucous membranes, e aofia ai le gutu, le vaʻa, le esophagus, le pusa leo, ma le ufiufi mata. O le tusitusiga e fautuaina ai o nisi ituaiga o le LP, e pei o le aafia i le esophagus po’o le mata, e le’i iloa atoatoa (underdiagnosed). O nisi ituaiga o le LP, e pei o le hypertrophic LP ma le erosive oral LP, e mafai ona mamafa tele ma umi le taimi o le maʻi. O isi mea e pei o vailaʻau po’o le fa’afeso’ota’i ma allergen e mafai ona fa’atupu i le lichenoid reaction, o le eseesega autu autu (main differential diagnosis) mo le LP.
Lichen planus (LP) is a chronic inflammatory disorder that most often affects middle-aged adults. LP can involve the skin or mucous membranes including the oral, vulvovaginal, esophageal, laryngeal, and conjunctival mucosa. It has different variants based on the morphology of the lesions and the site of involvement. The literature suggests that certain presentations of the disease such as esophageal or ophthalmological involvement are underdiagnosed. The burden of the disease is higher in some variants including hypertrophic LP and erosive oral LP, which may have a more chronic pattern. LP can significantly affect the quality of life of patients as well. Drugs or contact allergens can cause lichenoid reactions as the main differential diagnosis of LP.
Lichen Planus 10865927Lichen planus o se maʻi faʻamaʻi faʻaʻaveʻave, faʻamaʻi faʻavaʻi i le paʻu, naki, lau, ma le ʻauʻa o le mumu. E faʻailoa i le patupatu violē, mafolafola ma paʻepaʻe, ma e mafai ona matua mageso. O le masani ona afaina i lima i tua, i le faʻaletonu o le uapese ma le uapese i luga, i le tino, i le pito i lalo o le vae i le pito i tua, ma le ʻauʻa o le gutu. E leiloa le mafuaʻaga, ae e manatu e faʻatasi i se faiga faʻamaʻi faʻavaʻi ma se mea faʻataʻitaʻi leiloa. Ina ia faʻamaonia le faʻamaʻi cutaneous lichen planus, e mafai ona faia se suʻeina o le laʻau. O le immunofluorescence faʻatasi (DIF) e mafai ona fesoasoani i tagata o loʻo iai le paʻepaʻe bullous e faʻatusatusa lenei tulaga mai isi maʻi faʻavaʻi vesiculobullous. I tulaga ogaoga, oral lichen planus e ono faʻateleina le tulaga o le kanesa o le paʻu. E mafai foi ona afaina le ulu ma le fao. E ui o le tele o mataupu e leʻi iloa le mafuaʻaga, o nisi e ono faʻasoona e vailaʻau poʻo le maʻi hepatitis C. O le togafitiga e masani ona aofia ai kulimi malolosi mo le faʻamaʻi faʻapitonuʻu ma faʻamaʻi gutu mo le faʻamasani lautele.
Lichen planus is a skin condition marked by purplish, flat-topped bumps and patches that can cause intense itching. These skin lesions can be distressing, especially when they affect the mouth or genitals severely. In severe cases, oral lichen planus may even increase the risk of developing a type of skin cancer. It can also affect the scalp and nails. While the cause of most cases is unknown, some may be triggered by certain medications or hepatitis C infection. Treatment typically involves strong creams for localized cases and oral steroids for more widespread ones.
Oral lichen planus 32753462 NIH
Lichen planus o se fa’ama’i fa’aauau fa’ama’ale‑ma‑fa’ama’i, ua fa’a’afia e le immune system, ma a’afia le pa’u, vi’i, lauulu, ma le mucous membranes. E fa’ailoa i le polygonal, flat‑topped papules ma plaques ma le ‘scale’ pa’u mālū (Wickham’s striae). E masani ona o’afia i lima i tua, i le ufiufi o le ufiufi, i le forearm, i le tino, i le vae i lalo o le vae, ma le oral mucosa. E tusa ma le 5 % o tagata matutua, e masani lava i fafine, ma e masani ona amata i le vaeluagalemu o tausaga. E tusa ma le 77 % o tagata o lo’o iai le oral disease, o le buccal mucosa le nofoaga masani. E mafai ona le’i iai fa’ama’i i le oral, ae o nisi tagata e maua le tiga ma le fa’alavelave i mea’ai e pei o le acidic ma le spicy, ma le pa’u (toothpaste).
Lichen planus is an immune-mediated inflammatory condition leading to characteristic lesions on skin and mucous membranes. It presents in up to 5% of the general adult population with a female predilection (2:1); the onset is most commonly in middle age. Up to 77% of patients with lichen planus have oral disease, with buccal mucosa the most common subsite. The oral lesions may be asymptomatic, although a subset of patients have pain and difficulty tolerating certain foods (e.g., acidic, spicy) and toothpaste.
Ina ia faʻamaonia le lichen planus i le paʻu, e mafai ona faia se biopsy paʻu. Direct immunofluorescence (DIF) e mafai ona aoga i tagata ma le mauga o le paʻu (bullous lesions) e fa'ailoga ai lenei tulaga mai isi ma'i autoimmune vesiculobullous.